[Belgian register and reference centers for gestational trophoblastic diseases]

Area of Science:

• Gynecology
• Oncology
• Pathology

Context:

• Gestational trophoblastic diseases (GTDs) encompass a spectrum of placental pathologies, including hydatidiform moles and malignant neoplasms like choriocarcinoma.
• The low incidence and heterogeneity of GTDs often lead to suboptimal diagnosis and management.
• A national registration system with two reference centers has been established in Belgium to address these challenges.

Purpose:

• To establish a centralized system for the diagnosis, management, and treatment of gestational trophoblastic diseases in Belgium.
• To provide expert pathology review and guidance for physicians and patients.
• To facilitate individualized management strategies based on FIGO scoring and staging.

Summary:

• A national registration system and two reference centers in Belgium now manage gestational trophoblastic diseases.
• Expert pathology review, HCG monitoring, and FIGO staging guide individualized treatment.
• A multidisciplinary approach and a dedicated website (www.mole-chorio-bgog.eu) support practitioners and patients.

Impact:

• Improved diagnostic accuracy and consistency for rare placental pathologies.
• Standardized and optimized management protocols for gestational trophoblastic neoplasia.
• Enhanced collaboration between reference centers, physicians, and patients, supported by accessible information and a discussion forum.