Gestational Age at Term, Delivery Circumstance, and Their Association with Childhood Attention Deficit Hyperactivity

Nicole M Talge1, Dana M Allswede2, Claudia Holzman1

  • 1Department of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI.

Insights

Term-born children whose mothers had induced labor resulting in cesarean delivery showed higher attention deficit hyperactivity disorder (ADHD) symptoms. These findings highlight potential risks associated with specific delivery circumstances for childhood behavioral outcomes.

Area of Science:

  • Perinatal research
  • Child psychology
  • Obstetrics

Background:

  • Perinatal factors can indicate risks for academic and behavioral issues in term-born children.
  • Identifying at-risk subgroups is crucial for early intervention.

Purpose of the Study:

  • To investigate the association between perinatal characteristics (gestational age, delivery circumstance) and attention deficit hyperactivity disorder (ADHD) symptoms in term-born children.

Main Methods:

  • Utilized data from the Pregnancy Outcomes and Community Health Study.
  • Included 610 term-born children (ages 3-9) whose mothers completed the Conners' Parent Rating Scales-Revised-Short Form (CPRS-R-S).
  • Employed general linear models to assess delivery circumstances (labor onset, mode of delivery) and gestational age in relation to ADHD symptoms.

Main Results:

  • Children born after induced labor followed by cesarean delivery showed higher scores for inattention and the ADHD Index compared to spontaneous labor with vaginal delivery.
  • These associations were statistically significant after adjusting for parity, sociodemographics, and maternal mental health.
  • The observed effects were predominantly noted in male children.

Conclusions:

  • Induction of labor culminating in cesarean delivery was linked to elevated ADHD symptoms in term-born children.
  • Prenatal, antepartum, and/or postnatal factors related to this delivery profile may signify an increased risk for behavioral problems.
Abstract

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