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Disseminated Mycobacterium avium Complex With Cutaneous Lesions
Ramya Kollipara1, Kristen Richards2, Jaime Tschen3
1Texas Tech University Health Sciences Center, Lubbock, TX, USA sivaramya.kollipara@ttuhsc.edu.
Journal of Cutaneous Medicine and Surgery
|January 8, 2016
Summary
Disseminated Mycobacterium avium complex (MAC) infection can present with varied skin lesions in immunocompromised patients. Early diagnosis is crucial for effective, species-specific antibiotic treatment.
Area of Science:
- Infectious Diseases
- Dermatology
- Immunocompromised Hosts
Background:
- Disseminated Mycobacterium avium complex (MAC) is increasingly recognized in patients on immunosuppressive therapy, beyond those with human immunodeficiency virus (HIV).
- Cutaneous manifestations of disseminated MAC are diverse, including panniculitis, granulomas, pustules, and ulcerations.
Observation:
- This report details an atypical presentation of disseminated MAC infection with skin involvement.
- The case involves a patient who is immunocompromised due to iatrogenic causes, not HIV infection.
Findings:
- Diagnosis of MAC infection is complicated by nonspecific clinical signs and challenges in microbial culture.
- Acid-fast staining, while useful, is not specific for MAC identification.
Implications:
- Clinicians must consider MAC infection in patients presenting with acid-fast positive skin lesions, irrespective of HIV status.
- Prompt and accurate diagnosis is essential for initiating species-specific antibiotic regimens, improving patient outcomes.
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