Related Experiment Video

Updated: Mar 27, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

2.9K

Episodic Aphasia Associated With Cortical Spreading Depression After Subdural Hemorrhage Evacuation

Nirav H Shah1, David Adams1

  • 1Department of Neurology, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, USA.

The Neurohospitalist
|January 8, 2016
PubMed

Insights

Cortical spreading depression (CSD) can cause transient neurological symptoms mimicking stroke or seizures. This case highlights CSD diagnosis and treatment in a patient with post-surgical deficits.

Area of Science:

  • Neurology
  • Neuroscience

Background:

  • Cortical spreading depression (CSD) is implicated in various neurological conditions, including migraine and stroke.
  • Clinical diagnosis of CSD is challenging due to its mimicry of seizures and acute stroke.
  • CSD can present with transient focal neurological deficits.

Purpose of the Study:

  • To report a case of a patient with post-subdural hematoma evacuation who developed episodic neurological deficits.
  • To discuss the diagnostic approach and treatment strategies for suspected cortical spreading depression.
  • To emphasize the importance of considering CSD in the differential diagnosis of transient focal neurological deficits.

Main Methods:

  • Case report of a 77-year-old male patient.
  • Multimodal diagnostic approach to evaluate episodic aphasia and neurological deficits.
  • Review of clinical presentation, diagnostic workup, and treatment interventions.

Main Results:

  • The patient presented with episodic aphasia, slurred speech, and focal neurological deficits post-surgery.
  • A diagnosis of cortical spreading depression was proposed after ruling out other causes like stroke and seizures.
  • Treatment interventions demonstrated an impact on the resolution of CSD episodes.

Conclusions:

  • Cortical spreading depression should be considered in cases of brief, episodic focal neurological deficits, especially after stroke or seizures have been excluded.
  • A thorough diagnostic evaluation is crucial for identifying CSD.
  • Appropriate treatment can positively influence the outcome and resolution of CSD episodes.

Keywords:
cerebrovascular disorderscerebrovascular traumaclinical specialtydisordersheadacheimagingmigraine disordersnervous systemneurohospitalisttechniquestrauma

More Related Videos

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury09:16

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

Published on: June 21, 2019

26.5K
Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation09:01

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Published on: October 15, 2021

8.8K

Related Concept Videos

Dissociative Amnesia01:21

Dissociative Amnesia

Dissociative amnesia is a complex psychological condition that manifests as an inability to recall personal information, often tied to traumatic or stressful events. Unlike general amnesia, individuals with this condition retain the ability to perform routine activities and procedural tasks, such as operating a phone or navigating public transportation, yet experience profound gaps in autobiographical memory. These lapses may encompass significant life events, such as suicide attempts or...
949
Amnesia01:13

Amnesia

Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
801
Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
4.1K
Dissociative Disorders01:27

Dissociative Disorders

Dissociative disorders represent complex psychological conditions characterized by disruptions in consciousness, memory, identity, or perception. These disruptions cause individuals to experience a disconnection from their thoughts, emotions, and memories. The phenomenon is not merely an occasional lapse in attention but a profound alteration in mental functioning that can severely impact daily life.
Dissociative Fugue
A hallmark feature of dissociative disorders is the dissociative fugue...
884
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
10.4K