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Updated: Mar 27, 2026
13:08
Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
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Summary
Anticoagulation can prevent and treat venous thrombosis in pregnant women. While beneficial for acquired thrombophilia, its use in inherited thrombophilia with miscarriage history is debated.
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Thrombosis Research
Background:
- Thrombophilia poses risks during pregnancy, including venous thromboembolism.
- Understanding thrombophilia in pregnancy is crucial for maternal and fetal health.
Purpose of the Study:
- To provide a comprehensive overview of current knowledge on thrombophilia in pregnant women.
- To synthesize evidence regarding anticoagulation strategies for thrombophilia during pregnancy.
Main Methods:
- Literature review of available scientific sources.
- Overview study design analyzing existing data.
Main Results:
- Anticoagulation demonstrates efficacy in prophylaxis and treatment of venous thrombosis in pregnancy.
- Evidence supports anticoagulation for acquired thrombophilia during pregnancy.
Conclusions:
- Anticoagulation is recommended for pregnant women with acquired thrombophilia.
- The role of anticoagulation in inherited thrombophilia with a history of miscarriage requires further investigation.
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