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Updated: Mar 27, 2026

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma
Published on: November 19, 2019
The lymphatic system and pancreatic cancer
Darci M Fink1, Maria M Steele1, Michael A Hollingsworth1
1Eppley Institute, University of Nebraska Medical Center, Omaha, NE 68198-5950, USA.
Abstract:
This review summarizes current knowledge of the biology, pathology and clinical understanding of lymphatic invasion and metastasis in pancreatic cancer. We discuss the clinical and biological consequences of lymphatic invasion and metastasis, including paraneoplastic effects on immune responses and consider the possible benefit of therapies to treat tumors that are localized to lymphatics. A review of current techniques and methods to study interactions between tumors and lymphatics is presented.
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