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The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition

Loyse Hippolyte1, Anne M Maillard1, Borja Rodriguez-Herreros2

  • 1Service de Génétique Médicale, University of Lausanne, Lausanne, Switzerland.

Biological Psychiatry
|January 9, 2016
PubMed
Summary

Copy number variations in the 16p11.2 region impact cognitive skills differently. Deletion carriers show deficits in phonology and inhibition, while duplication carriers may have enhanced verbal memory and phonology.

Keywords:
16p11.2ASDCopy number variationInhibitionLanguageMemory

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