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Updated: Mar 27, 2026

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Retroperitoneal ancient schwannoma - case presentation.

Cristian Meşină1, Stelian Ştefăniţă Mogoantă, Daniel Alin Cristian

  • 1Department of Surgery, University of Medicine and Pharmacy of Craiova, Romania; mesina.cristian@doctor.com.

Romanian Journal of Morphology and Embryology = Revue Roumaine De Morphologie Et Embryologie
|January 9, 2016
PubMed
Summary

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Retroperitoneal ancient schwannomas, rare tumors, present unique diagnostic challenges. Complete surgical excision is the primary treatment, with good prognosis but a risk of recurrence.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Radiology

Background:

  • Retroperitoneal ancient schwannomas are rare neoplasms.
  • They are characterized by degenerative changes, calcifications, and fibrosis.
  • Typically found in the head, neck, and extremities, their retroperitoneal occurrence is infrequent.

Observation:

  • A 33-year-old male presented with a painful left iliac fossa mass.
  • Intraoperative findings revealed a cystic, encapsulated retroperitoneal mass.
  • Histopathological examination confirmed Schwann cells (Antoni A and B areas) and positive S100 protein.

Findings:

  • The diagnosis of ancient schwannoma was confirmed via immunohistochemistry.
  • Complete surgical excision is the recommended treatment.

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  • Schwannomas are resistant to radiotherapy and chemotherapy.

    • Implications:

    • Complete excision is crucial to minimize recurrence risk (5-10%).
    • Diagnosis relies on histopathology and immunohistochemistry post-surgery.
    • Retroperitoneal schwannomas are often incidentally discovered on imaging studies.