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Published on: May 19, 2020
Mitral valve prolapse: an overview
1George Washington University School of Medicine and Health Sciences, Washington, D.C. 20037.
Insights
Mitral valve prolapse (MVP) is a common heart condition, often affecting women and younger individuals. While generally having an excellent prognosis, potential complications like heart valve issues and stroke require monitoring.
Area of Science:
- Cardiology
- Valvular Heart Disease
- Clinical Medicine
Background:
- Mitral valve prolapse (MVP) is a prevalent global heart condition, recognized for over 25 years.
- It disproportionately affects women, thinner individuals, and younger populations.
- A valvular-ventricular disproportion concept unifies various MVP presentations.
Purpose of the Study:
- To review the epidemiology, etiology, diagnosis, and prognosis of mitral valve prolapse.
- To discuss the multifactorial causes of chest pain in MVP patients.
- To highlight surgical preferences for MVP complications.
Main Methods:
- Clinical auscultation is the primary diagnostic method for MVP.
- Echocardiography, angiocardiography, and radionuclide ventriculography serve as valuable diagnostic adjuncts.
- Review of existing literature on MVP etiology, symptoms, and outcomes.
Main Results:
- Chest pain is the most frequent presenting symptom, with multifactorial etiology.
- Prognosis is typically excellent, barring complications such as progressive mitral regurgitation, infective endocarditis, cerebral ischemia, or sudden death.
- Surgical repair is favored over replacement for mitral valve surgery.
Conclusions:
- Mitral valve prolapse is a common condition with a generally favorable prognosis.
- Early diagnosis through auscultation and imaging is crucial.
- Management focuses on monitoring for complications and preferring valve repair during surgery.
Abstract:
Since its original description by Barlow over a quarter of a century ago, mitral valve prolapse has become one of the commonest heart diseases around the world. It is commoner in women than men, in thinner than heavier subjects, and in younger than older persons. A unifying concept of a valvular-ventricular disproportion serves to explain the various conditions in which mitral valve prolapse occurs. The etiology of chest pain which is the most frequent symptom that brings the patient with mitral valve prolapse to a physician is multifactorial. Diagnosis of mitral valve prolapse is based on clinical grounds chiefly by careful auscultation. Echocardiography, angiocardiography, and radionuclide ventriculography are valuable adjuncts. Prognosis in the majority is excellent except when complications occur, such as progressive mitral regurgitation, infective endocarditis, cerebral ischemic episodes, and sudden death. For mitral valve surgery repair is preferred to replacement.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Valve Prolapse III: Nursing Management
Mitral Regurgitation I: Introduction
Mitral Stenosis I: Introduction
Mitral Stenosis III: Medical Management

