Related Experiment Video
Updated: Mar 27, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Dietary patterns in weight loss maintenance: results from the MedWeight study
Eleni Karfopoulou1, Dora Brikou1, Eirini Mamalaki1
1Department of Nutrition and Dietetics, Harokopio University, El. Venizelou 70, 17671, Athens, Greece.
Successful weight loss maintenance is linked to specific dietary and lifestyle habits. Men who maintained weight loss were more likely to eat a healthy diet, prepare meals, and eat at home.
Area of Science:
- Obesity research
- Nutritional science
- Behavioral medicine
Background:
- Understanding the behaviors associated with long-term weight loss maintenance is crucial for effective obesity treatment.
- Previous research has not fully elucidated the specific lifestyle factors differentiating weight loss maintainers from those who regain weight.
Purpose of the Study:
- To identify and compare the dietary and lifestyle behaviors of individuals who have successfully maintained weight loss with those who have regained weight.
- To pinpoint actionable strategies for improving obesity management through targeted behavioral interventions.
Main Methods:
- The MedWeight study utilized questionnaires and two 24-hour dietary recalls to assess lifestyle habits and dietary intake in Greek participants.
- Participants were categorized as weight loss maintainers (≥10% weight loss for >1 year) or regainers.
- Statistical analyses, including principal component analysis, were employed to identify differentiating behaviors.
Main Results:
- No significant differences in overall energy or macronutrient intake were observed between maintainers and regainers.
- Maintainers, particularly men, showed higher protein intake per kilogram of body weight and greater physical activity energy expenditure.
- A healthy dietary pattern (unprocessed cereals, fruits, vegetables, olive oil, low-fat dairy) was strongly associated with weight loss maintenance in men. Eating at home, meal preparation, higher eating frequency, and slower eating rates were also linked to maintenance.
Conclusions:
- Adherence to a healthy dietary pattern is a key factor for men in maintaining weight loss.
- Lifestyle behaviors such as eating at home, preparing meals, and mindful eating practices (higher frequency, slower rate) are associated with successful weight loss maintenance.
- These identified behaviors offer potential targets for interventions aimed at improving obesity treatment outcomes.
Related Concept Videos
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Drug Dosing: Obese Patients
Regulation of Food Intake
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Chronic Kidney Disease III: Interprofessional Care
Dietary Connections

