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Proofreading01:43

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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
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Want a letter? You write it for me

Roger S Day1

  • 1Roger S. Day is an associate professor of biomedical informatics and biostatistics at the University of Pittsburgh in Pennsylvania. Send your story to SciCareerEditor@aaas.org.

Science (New York, N.Y.)
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No abstract available in PubMed .

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