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Updated: Mar 27, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Introduction: Male fertility preservation: innovations and questions
René Frydman1, Michaël Grynberg2
1University Paris V, Paris, France; Service de Gynécologie Obstétrique, Hôpital Foch, Suresnes, France.
Abstract:
It is now well established that many benign or malignant diseases may by themselves or as result of treatment, impair male fertility. Therefore, preserving the potential of becoming a genetic father represents a major issue. Besides sperm cryopreservation, which is the most reliable method for male fertility preservation, other strategies have more recently emerged, especially in prepubertal boys. Prepubertal germ cell storage from testicular sperm extraction and derivation of male gametes from stem cells may represent a future hope, although raising many ethical issues.
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