Related Experiment Video
Updated: Mar 27, 2026
05:06
Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise
Published on: July 14, 2023
2.6K
Diabetes and cervical myelopathy.
John K Houten1, Christopher Lenart2
1Marcus Neuroscience Institute at the Boca Raton Regional Hospital, Boca Raton, FL 33486, USA.
Summary
Diabetes can alter physical signs in cervical spondylotic myelopathy (CSM). Diabetic patients may show hyporeflexia and a positive Babinski sign, aiding diagnosis.
Area of Science:
- Neurology
- Orthopedics
- Endocrinology
Background:
- Cervical spondylotic myelopathy (CSM) is a common spinal cord compression condition.
- Diabetes can cause neuropathy, potentially altering neurological examination findings.
- Few studies have investigated how diabetes affects the presentation of CSM.
Purpose of the Study:
- To compare the presenting neurological signs and symptoms of surgically treated CSM patients with and without diabetes.
- To evaluate the impact of diabetes on clinical outcomes after CSM surgery.
Main Methods:
- Retrospective study of 438 patients surgically treated for CSM.
- Comparison of neurological signs, symptoms, and outcomes between 79 diabetic and 359 non-diabetic patients.
- Preoperative modified Japanese Orthopaedic Association (mJOA) scores and specific reflex assessments were analyzed.
Main Results:
- Diabetic patients were older and had lower preoperative mJOA scores.
- A higher incidence of hyporeflexia and a positive Babinski sign was observed in diabetic patients.
- Surgical outcomes, measured by mJOA improvement, were comparable between groups.
Conclusions:
- Diabetes can alter the typical physical findings in cervical spondylotic myelopathy.
- Recognizing these differences, such as hyporeflexia and Babinski sign, may improve diagnostic accuracy for CSM in diabetic individuals.
Related Concept Videos
01:15Diabetes: Symptoms, Diagnosis, and Complications
2.7K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.7K
01:22Diabetes Mellitus: Type 2 and Gestational
5.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.5K
01:19Psychoneuroimmunology: Diabetes and Cancer
630
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
630
01:20Pathophysiology of Diabetes
4.3K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.3K
01:22Diabetes Mellitus: Overview and Type I Subtype
5.9K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
5.9K
01:36Carbohydrate Metabolism
15.0K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
15.0K