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Clinical pharmacology of CAR-T cells: Linking cellular pharmacodynamics to pharmacokinetics and antitumor effects

M Norelli1, M Casucci2, C Bonini3

  • 1Innovative Immunotherapies Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Hospital Scientific Institute, Milano, Italy; Vita-Salute San Raffaele University, Milano, Italy.

Biochimica Et Biophysica Acta
|January 10, 2016
PubMed

Keywords:
Adoptive cell transferCancer immunotherapyClinical resultsGenetically modified T cellsPharmacokinetics/pharmacodynamicsToxicities

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