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Eomesodermin promotes interferon-γ expression and binds to multiple conserved noncoding sequences across the Ifng

Natsuki Fukuoka1, Misuzu Harada1, Ai Nishida1

  • 1Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto, 606-8585, Japan.

Genes to Cells : Devoted to Molecular & Cellular Mechanisms
|January 11, 2016
PubMed
Summary

Eomesodermin (Eomes) induces interferon-gamma (IFN-γ) production in cells lacking T-bet. Eomes binds the Ifng promoter and regulatory regions, influencing IFN-γ expression.

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