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Updated: Mar 27, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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Published on: October 4, 2019

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Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial

Johan Andersen-Ranberg1, Kenneth Thermann Kongstad2, Morten Thrane Nielsen1

  • 1Department of Plant and Environmental Sciences, Center for Synthetic Biology, Thorvaldsensvej 40, 1871, København, Denmark.

Angewandte Chemie (International Ed. in English)
|January 11, 2016
PubMed
Summary

Researchers engineered yeast to produce novel plant diterpenoids. This scalable biotechnological approach creates new-to-nature compounds for pharmaceuticals and fragrances, overcoming limitations of low natural abundance.

Keywords:
biocatalysisbiosynthesiscombinatorial biosynthesiscyclizationsterpenes

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