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Related Concept Videos

Hypodermis01:02

Hypodermis

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The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
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Loose Connective Tissue01:26

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Loose connective tissue is found between many organs. Its main function is to absorb shock and bind tissues together. It also allows water, salts, and various nutrients to diffuse into cells that are embedded in it or present in adjacent tissues.
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Related Experiment Video

Updated: Mar 27, 2026

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images
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Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

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[Human brown adipose tissue].

Kirsi A Virtanen, Pirjo Nuutila

    Duodecim; Laaketieteellinen Aikakauskirja
    |January 12, 2016
    PubMed
    Summary
    This summary is machine-generated.

    Brown adipose tissue (BAT) in adult humans generates heat and consumes energy. Its metabolism increases in the cold, particularly in young, normal-weight women, suggesting a role in energy expenditure.

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    Area of Science:

    • Human physiology
    • Adipose tissue biology
    • Metabolic research

    Background:

    • Adult humans possess heat-producing brown adipose tissue (BAT) in the neck's clavicular region.
    • BAT comprises classic and beige adipocytes, utilizing fatty acids and sugar for thermogenesis via uncoupling protein 1 (UCP1).

    Purpose of the Study:

    • To investigate the metabolic activity of brown adipose tissue in adult humans.
    • To explore factors influencing brown fat activation and its potential role in energy consumption.

    Main Methods:

    • Utilized positron emission tomography (PET) to measure glucose uptake, a proxy for metabolic activity.
    • Assessed brown fat metabolism under conditions potentially influencing its activation.

    Main Results:

    • Brown fat metabolism significantly increases in cold conditions, as indicated by heightened sugar utilization.
    • Active brown fat is more prevalent in young adults, individuals with normal weight, and women.
    • Obese individuals appear to have less active brown fat.

    Conclusions:

    • Cold exposure stimulates brown adipose tissue metabolism in humans.
    • Demographic and body composition factors influence brown fat activity, with implications for energy balance.