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Updated: Mar 27, 2026
Author Spotlight: Exploring the Potential of Fat-Derived Stromal Vascular Fraction for Wound Healing
Published on: November 17, 2023
[RESEARCH PROGRESS OF TISSUE ENGINEERED SCAFFOLDS AND STROMAL-DERIVED FACTOR 1 COMPOSITE GRAFT]
Objective:
To review the research progress of tissue engineered scaffolds and stromal-derived factor 1 (SDF-1) composite graft.
Methods:
The recent papers about SDF-1 with different kinds of tissue engineered scaffolds were reviewed and analyzed. The primary mechanism of SDF-1 homing function for stem cells was retrospected. The results of different kinds of tissue engineered scaffolds carrying SDF-1 for repairing the injured tissues and organs were reviewed.
Results:
It is shown that SDF-1 combined with tissue engineered scaffolds will play a role of multipotent stem cells chemotaxis, however, the exact chemotaxis mechanism has not been fully understood. It still needs more researches of SDF-1 effects in vivo.
Conclusion:
Although some research progress has been made in regeneration in situ of tissue engineered scaffolds combined with SDF-1, it will need to further study on the mechanism of chemotactic functions of SDF-1 and its influence on proliferation and differentiation of cells.
