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Adverse birth outcomes and childhood caries: a cohort study
Areerat Nirunsittirat1, Waranuch Pitiphat2,3, Christy Michelle McKinney4
1Graduate School, Khon Kaen University, Khon Kaen, Thailand, and Department of Family and Community Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Insights
Preterm birth showed an inverse association with childhood dental caries. However, low birthweight and small-for-gestational age were not linked to cavities in primary teeth in this Thai cohort.
Area of Science:
- Pediatric Dentistry
- Neonatal Health
- Public Health
Background:
- Adverse birth outcomes are potential risk factors for childhood diseases.
- Dental caries is a prevalent childhood disease with multifactorial etiology.
Purpose of the Study:
- To investigate the association between adverse birth outcomes (preterm birth, low birthweight, small-for-gestational age) and the presence of dental caries in primary teeth.
Main Methods:
- A cohort of 758 children from Khon Kaen, Thailand, was analyzed.
- Dental caries was assessed using the decayed, missing, and filled surfaces (dmfs) index in children aged 3-4 years.
- Negative binomial regression models were used to estimate adjusted relative risks.
Main Results:
- Dental caries was prevalent, affecting 88.2% of children with a mean dmfs of 14.3.
- An inverse association was found between preterm birth and dental caries (adjusted RR 0.61).
- Low birthweight (LBW) and small-for-gestational age (SGA) were not significantly associated with dental caries.
Conclusions:
- Preterm birth may have a protective association with childhood dental caries.
- LBW and SGA do not appear to be risk factors for dental caries in this population.
Objectives:
To examine the association between adverse birth outcomes and dental caries in primary teeth.
Methods:
This study included children in Khon Kaen, Thailand, who participated in the Prospective Cohort Study of Thai Children. Preterm was defined as a birth at <37 weeks gestation, low birthweight (LBW) as birthweight <2500 g, and small-for-gestational age (SGA) as birthweight <10th percentile of expected weight for gestational age. Two calibrated dentists measured dental caries in primary teeth when the children were 3-4 years old using decayed, missing and filled surfaces (dmfs) index following the World Health Organization criteria. We used negative binomial regression with generalize linear models to estimate relative risks (RRs) and their 95% confidence intervals (CIs), adjusted for confounding factors. Of 758 children with gestational age data and 833 with birthweight data, the 544 (follow-up rate of 71.8% in preterm and 65.3% in LBW) who had dental data available were included in the analysis.
Results:
Dental caries was observed in 480 children (88.2%), with a mean dmfs of 14.3 (standard deviation 12.8). The adjusted RR for dental caries was 0.61 (95% CI 0.43, 0.85) for preterm, 0.89 (95% CI 0.67, 1.21) for LBW, and 0.96 (95% CI 0.74, 1.26) for SGA.
Conclusions:
There was an inverse association between preterm and childhood caries. LBW and SGA were not associated with dental caries in this population.
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