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Protection by recombinant human superoxide dismutase in lethal rat endotoxemia
J Schneider1, E Friderichs, H Giertz
1Department of Pharmacology, Grünenthal GmbH, Aachen, FRGermany.
Progress in Clinical and Biological Research
|January 1, 1989
Abstract:
In summary as mechanism of the overall protective effect of r-HSOD in lethal rat endotoxemia, inhibition of hemoconcentration, a tendency of a decreased leukocyte activation and attenuation of consumption coagulopathy could be established.