Fluorescent supramolecular nanoparticles signal the loading of electrostatically charged cargo
Laura Graña-Suárez1, Willem Verboom, Jurriaan Huskens
1Molecular Nanofabrication group, MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands. w.verboom@utwente.nl j.huskens@utwente.nl.
Chemical Communications (Cambridge, England)
|January 12, 2016
Abstract:
Fluorescently labeled supramolecular nanoparticles (SNPs) were used to study the effects of their loading with oppositely charged cargo. SNPs shrank until neutralization, upon which they destabilized and aggregated. Using a dye-labelled guest, FRET occurred between the SNPs and a dye-labeled cargo. This effect may allow the development of responsive imaging and drug delivery vehicles.
