Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Transformation

Transformation

Microbial communities are dynamic environments where cell lysis releases free DNA into the surroundings. Other cells can take up this extracellular DNA through a process known as transformation.When a cell incorporates this foreign DNA into its genome, resulting in genetic modification, the process is known as transformation. Cells capable of this process are termed competent. Competence can be natural, as observed in certain bacteria and archaea, or artificially induced in the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The need to strengthen laboratory leadership, systems, and networks to enhance outbreak detection and resilience in Africa: proceedings of a regional workshop.

BMC proceedings·2026

Same author

Measuring capacities to advance global health security and bioeconomic development on the African continent.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026

Same author

The role of artificial intelligence in diagnostics: A new frontier for laboratory medicine in Africa.

African journal of laboratory medicine·2025

Same author

Two years of COVID-19 in Africa: lessons for the world.

Nature·2025

Same author

Assessing operational readiness: Regulatory landscape and compliance in zimbabwe for medical devices and in vitro diagnostic medical devices.

PloS one·2024

Same author

Navigating regulatory landscape: A qualitative exploration of medical devices and in vitro diagnostic medical devices oversight in Zimbabwe through key stakeholder perspectives.

PloS one·2024

Same journal

Burden of rare genetic variants in genes associated with cancer among Malawian cervical cancer patients.

African journal of laboratory medicine·2026

Same journal

The road map for ISO 15189-laboratory accreditation: The Experience of Manhiça Health Research Centre (CISM) laboratory, in southern Mozambique.

African journal of laboratory medicine·2026

Same journal

Friedewald and Martin-Hopkins formulae for estimating low-density lipoprotein cholesterol in a Malagasy population.

African journal of laboratory medicine·2026

Same journal

Whole-genome sequencing for surveillance of <i>Salmonella</i> at a public health institution in South Africa.

African journal of laboratory medicine·2026

Same journal

Age- and gender-based frequency and association of common myeloproliferative mutations in a South African cohort.

African journal of laboratory medicine·2026

Same journal

The β-goblin gene architecture in individuals with and without sickle cell disease in Nigeria: Implications for β-thalassaemia trait diagnosis.

African journal of laboratory medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 27, 2026

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

The SLMTA programme: Transforming the laboratory landscape in developing countries.

Katy Yao¹, Talkmore Maruta², Elizabeth T Luman¹

¹International Laboratory Branch, Division of Global HIV/AIDS, US Centers for Disease Control and Prevention (CDC), Atlanta, United States.

African Journal of Laboratory Medicine

|January 12, 2016

Summary

This summary is machine-generated.

Strengthening Laboratory Management Toward Accreditation (SLMTA) is an innovative training program that improves laboratory services in developing countries. It connects management practices to ISO 15189 standards, aiding laboratories in seeking accreditation.

More Related Videos

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

Related Experiment Videos

Last Updated: Mar 27, 2026

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

Area of Science:

Laboratory Management
Health Systems Strengthening
Quality Improvement

Background:

Efficient laboratory services are crucial for effective healthcare systems.
Laboratory managers are key to service quality and timeliness.
Existing programs often lack focus on resource-limited settings.

Purpose of the Study:

To describe the Strengthening Laboratory Management Toward Accreditation (SLMTA) program.
To highlight achievements, challenges, and lessons learned from its implementation.
To showcase an innovative approach to laboratory management training.

Main Methods:

SLMTA is a competency-based program with short courses and work-based projects.
Training spans 12-18 months, including project implementation and supervision.
Audits use the WHO AFRO Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA) checklist, based on ISO 15189.

Main Results:

SLMTA was implemented in 617 laboratories across 47 countries within five years.
The program demonstrated immediate and measurable laboratory improvements.
Participants were empowered to implement practical quality management systems.

Conclusions:

SLMTA is the first program explicitly linking management behaviors to ISO 15189 requirements.
The program significantly transformed laboratory services in developing countries.
SLMTA uniquely positions laboratories to pursue ISO 15189 accreditation.