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Published on: January 7, 2019
Vascular graft infection due to Pasteurella multocida
F Fourreau1, F Méchaï2, J Brossier3
1Service de médecine interne, CHU Kremlin Bicêtre/Assistance publique-hôpitaux de Paris et Université Paris, Sud 78, rue du générale Leclerc, Le Kremlin Bicetre, 94270 France.
Background:
Vascular graft infections are infrequent complications with important morbidity and mortality rates. Pasteurella multocida, a Gram negative bacillus, is a normal oral commensal of many animals. For mankind, it is a pathogenous bacillus which is rarely implicated in vascular grafts.
Case Report:
We report hereafter the fourth case introduced in the international literature about vascular graft infections caused by P. multocida. The patient was successfully treated with a combination of a surgical graft change and a 6 weeks bi-antibiotic therapy.
Discussion:
There is fours case reported in litterature with quite different antibiotic drugs and duration.
Conclusion:
P. multicoda graft infection should be long with initial intravenous drug and mainteance traitement should not be required.
Insights
Vascular graft infections caused by Pasteurella multocida are rare. Successful treatment involved surgical graft replacement and a six-week antibiotic regimen, highlighting a potential management approach for this uncommon infection.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Microbiology
Background:
- Vascular graft infections are uncommon but serious complications.
- Pasteurella multocida, a Gram-negative bacillus, is a common animal oral commensal and a rare human pathogen.
- This bacterium is infrequently associated with vascular graft infections.
Purpose of the Study:
- To report the fourth case of vascular graft infection caused by Pasteurella multocida in the literature.
- To describe the successful management of such an infection.
Main Methods:
- Surgical intervention involving graft replacement.
- A six-week course of bi-antibiotic therapy.
Main Results:
- Successful treatment outcome achieved with the combined approach.
- This case adds to the limited documented instances of P. multocida vascular graft infections.
Conclusions:
- Pasteurella multocida vascular graft infections require prolonged treatment.
- Initial intravenous antibiotic therapy followed by maintenance treatment may be necessary.
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