Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

4.1K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
4.1K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.4K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.4K
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

619
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
619
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

3.6K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.6K
Common Respiratory Disorders01:31

Common Respiratory Disorders

1.8K
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.8K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

5.0K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
5.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Life-Context Factors on Chronic Rhinosinusitis 22-Item Sinonasal Outcomes Test: Systematic Review + Meta-Analysis.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same author

Single-layer Endoscopic Repair of Anterior Skull Base Defects.

Otolaryngologic clinics of North America·2026
Same author

Contemporary Perspectives on Management of Skull Base Cerebrospinal Fluid Leaks.

Otolaryngologic clinics of North America·2026
Same author

Two-Year Clinical Outcomes After Multipoint Impedance-Controlled Radiofrequency Ablation of the Posterior Nasal Nerve for Treatment of Chronic Rhinitis.

Ear, nose, & throat journal·2025
Same author

Modified uvulopalatopharyngoplasty in modern obstructive sleep apnea treatment: a narrative review.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2025
Same author

Expert Strategies: Skull Base Reconstruction-Global Perspectives, Insights, and Algorithms through a Mixed Methods Approach.

International forum of allergy & rhinology·2025

Related Experiment Video

Updated: Mar 27, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.7K

Functional Comorbidity Index in chronic rhinosinusitis.

Corinna G Levine1, Greg E Davis1, Edward M Weaver1,2

  • 1Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, WA.

International Forum of Allergy & Rhinology
|January 13, 2016
PubMed
Summary

The Functional Comorbidity Index better predicts general health status in chronic rhinosinusitis patients than the Charlson Comorbidity Index. This finding supports its use for assessing health in these patients.

Keywords:
comorbidityconfounding factorshealth statusoutcomes researchsinusitis

More Related Videos

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.2K
Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.8K

Related Experiment Videos

Last Updated: Mar 27, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.7K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.2K
Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.8K

Area of Science:

  • Medical research
  • Clinical outcomes assessment
  • Health status measurement

Background:

  • The Functional Comorbidity Index (FCI) shows promise for predicting general health and adjusting for confounding in chronic condition studies.
  • Previous validation of the FCI was limited to a sleep apnea cohort.
  • The FCI's utility in chronic rhinosinusitis (CRS) requires further investigation.

Purpose of the Study:

  • To assess the association between the FCI and general health status (SF-36 PCS/MCS) in CRS patients.
  • To compare the predictive power of the FCI against the Charlson Comorbidity Index (CCI) for general health status in CRS.

Main Methods:

  • A cross-sectional study involving 97 chronic rhinosinusitis patients.
  • Collected data on FCI, CCI, and SF-36 scores.
  • Employed Spearman correlations and multiple linear regression with bootstrapping for statistical analysis.

Main Results:

  • FCI scores (2.2 ± 1.9) showed wider distribution than CCI scores (0.6 ± 1.2).
  • FCI significantly correlated with SF-36 Physical Component Score (PCS) (-0.49) and Mental Component Score (MCS) (-0.37).
  • FCI demonstrated superior prediction of SF-36 PCS (R(2)=0.21) and MCS (R(2)=0.16) compared to CCI (PCS R(2)=0.15, MCS R(2)=0.01).

Conclusions:

  • The Functional Comorbidity Index is a more robust predictor of general health status in chronic rhinosinusitis patients.
  • FCI offers improved assessment of health status compared to the Charlson Comorbidity Index in this population.