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Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

7.6K
A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

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Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
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Methods of reducing fever01:22

Methods of reducing fever

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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
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In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System
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In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System

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Hyperthermia using nanoparticles--Promises and pitfalls.

Punit Kaur1, Maureen L Aliru2,3, Awalpreet S Chadha2

  • 1a Department of Microbiology, Biochemistry and Immunology , Morehouse School of Medicine , Atlanta , Georgia , USA .

International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
|January 14, 2016
PubMed
Summary
This summary is machine-generated.

Mild temperature hyperthermia sensitizes tumors to conventional therapies. Nanoparticles offer a novel approach to hyperthermia, providing unique opportunities and challenges for cancer treatment.

Keywords:
Cancerhyperthermiananoparticles

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Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods
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Area of Science:

  • Oncology
  • Biomedical Engineering
  • Materials Science

Background:

  • Growing evidence supports hyperthermia's role in enhancing chemotherapy and radiation therapy efficacy.
  • Technological advancements focus on precise temperature control for hyperthermia applications.
  • Nanotechnology presents a new frontier in hyperthermia treatment delivery.

Purpose of the Study:

  • To review nanoparticle-based hyperthermia for cancer treatment.
  • To discuss nanoparticle types, activation methods, and properties.
  • To explore the potential and challenges of nanoparticle-mediated hyperthermia.

Main Methods:

  • Literature review of nanoparticles for hyperthermia.
  • Analysis of nanoparticle activation sources (e.g., magnetic fields, light).
  • Evaluation of nanoparticle characteristics relevant to heat generation and biological interaction.

Main Results:

  • Various nanoparticles are available for hyperthermia generation.
  • Extrinsic energy sources are used to activate nanoparticles.
  • Nanoparticle properties influence heat generation and therapeutic outcomes.

Conclusions:

  • Nanoparticle-mediated hyperthermia is a promising area in cancer therapy.
  • Careful selection of nanoparticles and activation methods is crucial.
  • Further research is needed to overcome challenges and optimize clinical translation.