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[Clinical features of protracted bacterial bronchitis in children]

Fanfan Chi1, Yuqing Wang, Chuangli Hao2

  • 1Department of Respiratory Diseases, Children's Hospital of Soochow University, Suzhou 215003, China.

Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics
|January 14, 2016
PubMed

Insights

Protracted bacterial bronchitis (PBB) in children is often characterized by persistent wet cough with wheezing, primarily affecting male infants. Treatment with antibiotics typically leads to a good prognosis.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Protracted bacterial bronchitis (PBB) is a common cause of chronic wet cough in children.
  • Understanding the clinical profile of PBB is crucial for timely diagnosis and effective management.

Purpose of the Study:

  • To analyze the clinical characteristics of protracted bacterial bronchitis (PBB) in pediatric patients.
  • To identify common pathogens and associated conditions in PBB.

Main Methods:

  • Retrospective analysis of clinical data from pediatric patients diagnosed with PBB.
  • Inclusion criteria included prolonged cough, bronchoscopy findings, and positive bacterial culture or elevated neutrophils in bronchoalveolar lavage fluid (BALF).

Main Results:

  • PBB predominantly affected male infants, presenting with persistent wet cough and wheezing.
  • Common pathogens identified were Streptococcus pneumoniae and Haemophilus influenzae.
  • Airway malacia and immune dysfunction were frequently observed comorbidities.

Conclusions:

  • PBB is characterized by persistent wet cough with wheezing, particularly in male infants.
  • Streptococcus pneumoniae and Haemophilus influenzae are the primary causative agents.
  • PBB often coexists with immune dysfunction and airway malacia, necessitating targeted treatment.
Abstract

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