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Updated: Mar 27, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Exercise echocardiography for structural heart disease
Masaki Izumo1, Yoshihiro J Akashi2
1Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, 216-8511, Japan. heartizumo@yahoo.co.jp.
Insights
Exercise echocardiography aids in assessing structural heart disease, particularly aortic stenosis and mitral regurgitation. This review highlights its clinical value and prognostic impact for these common valvular conditions.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- Structural heart disease encompasses congenital, valvular, and cardiomyopathic conditions.
- Valvular heart disease, including aortic stenosis (AS) and mitral regurgitation (MR), is increasingly prevalent in aging populations.
- Transcatheter interventions are common for AS and MR, necessitating accurate diagnostic tools.
Purpose of the Study:
- To review the clinical utility of exercise echocardiography in structural heart disease.
- To evaluate the prognostic impact of exercise echocardiography, specifically for aortic stenosis and mitral regurgitation.
Main Methods:
- Review of existing literature on exercise echocardiography for structural heart disease.
- Focus on applications in aortic stenosis and mitral regurgitation assessment.
Main Results:
- Echocardiography is the standard for AS and MR diagnosis, but challenges remain.
- Exercise echocardiography offers valuable insights beyond resting assessments.
- The prognostic information provided by exercise echocardiography is significant.
Conclusions:
- Exercise echocardiography is a valuable tool for evaluating patients with structural heart disease.
- Its clinical usefulness and prognostic impact are particularly relevant for aortic stenosis and mitral regurgitation.
Abstract:
Since the introduction of transcatheter structural heart intervention, the term "structural heart disease" has been widely used in the field of cardiology. Structural heart disease refers to congenital heart disease, valvular heart disease, and cardiomyopathy. In structural heart disease, valvular heart disease is frequently identified in the elderly. Of note, the number of patients who suffer from aortic stenosis (AS) and mitral regurgitation (MR) is increasing in developed countries because of the aging of the populations. Transcatheter aortic valve replacement and percutaneous mitral valve repair has been widely used for AS and MR, individually. Echocardiography is the gold standard modality for initial diagnosis and subsequent evaluation of AS and MR, although the difficulties in assessing patients with these diseases still remain. Here, we review the clinical usefulness and prognostic impact of exercise echocardiography on structural heart disease, particularly on AS and MR.
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