Related Experiment Video
Updated: Mar 27, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Livedoid vasculopathy: fast involution after anticoagulant and hyperbaric oxygen therapy
Patricia Weinschenker Bollmann1, Andréa Kazumi Shimada2, Nilceo Schwery Michalany3
1Hematology and Bone Marrow Transplantation, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
Livedoid vasculopathy, a rare cause of leg ulcers, may improve with anticoagulation and hyperbaric oxygen therapy. This combined treatment showed significant healing in a patient with this painful condition.
Area of Science:
- Vascular Medicine
- Dermatology
- Hematology
Background:
- Livedoid vasculopathy is a rare condition causing painful leg ulcers.
- Histology shows thickened dermal vessels occluded by fibrin thrombi.
- It can be isolated or linked to systemic diseases like coagulation disorders.
Purpose of the Study:
- To report a case of livedoid vasculopathy.
- To evaluate the efficacy of anticoagulation and hyperbaric therapy.
Main Methods:
- A case study of a 41-year-old male patient.
- Treatment involved anticoagulant therapy and hyperbaric oxygen therapy.
- No underlying systemic diseases were identified.
Main Results:
- The patient presented with recurrent, painful ulcers on the lower extremities.
- Significant improvement in ulcer healing was observed after treatment.
- No associated systemic diseases were found.
Conclusions:
- Anticoagulation combined with hyperbaric oxygenation may benefit livedoid vasculopathy patients.
- Further research with larger populations is needed to confirm these findings.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis IV: Nursing Management
Venous Thrombosis I: Introduction
Varicose Veins I: Introduction

