Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

26.9K
Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
26.9K
Interpersonal Psychotherapy01:25

Interpersonal Psychotherapy

567
Interpersonal psychotherapy (IPT) is a structured, time-limited therapeutic approach initially developed to treat depression. It integrates key concepts from psychodynamic, humanistic, and cognitive-behavioral therapies, making it a uniquely eclectic framework. The therapy is rooted in the interpersonal theories of Adolph Meyer and Harry Stack Sullivan, as well as John Bowlby's attachment theory, and focuses on the interplay between interpersonal relationships and emotional well-being.
567
Behavior Therapy01:22

Behavior Therapy

929
Behavior therapy incorporates diverse techniques rooted in classical conditioning principles to address maladaptive behaviors and anxiety disorders. These methods aim to reduce avoidance behaviors, foster adaptive coping mechanisms, and alter associations between stimuli and responses, making them effective in a wide range of therapeutic contexts.
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
929
Modeling in Therapy01:26

Modeling in Therapy

695
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
695
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors01:28

Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

715
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
715
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

2.0K
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Testosterone abuse in Brazil: a growing public health challenge.

Clinics (Sao Paulo, Brazil)·2026
Same author

Assessment Instruments for Social Anxiety in Oral and Public Communication Among Health Sciences Students: Protocol for a Scoping Review.

JMIR research protocols·2026
Same author

Return to work outcomes in solid organ transplant recipients: A protocol for a global scoping review.

PloS one·2026
Same author

Strengthening Undergraduate Medical Education for Inclusive Health Care for People With Down Syndrome and Intellectual and Developmental Disabilities in Medical Schools: Protocol for a Scoping Review.

JMIR research protocols·2026
Same author

Prolonged Effects on Frontline Caregivers: Occupational Stress and Mental Well-Being in Transformed Healthcare Environments Post-COVID-19.

International journal of environmental research and public health·2026
Same author

Cost-Effectiveness Analysis of Medications in the Field of Sexual Medicine Offered by the Brazilian Universal Healthcare System at a Tertiary Hospital.

Cureus·2025

Related Experiment Video

Updated: Mar 27, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

1.3K

Premature ejaculation: is there an efficient therapy?

Fábio Barros de Francischi1, Daniel Cernach Ayres1, Ricardo Eidi Itao1

  • 1Hospital de Base, Faculdade de Medicina de São José do Rio Preto - FAMERP, São José do Rio Preto, SP, BR.

Einstein (Sao Paulo, Brazil)
|January 14, 2016
PubMed
Summary
This summary is machine-generated.

Premature ejaculation affects many men. While behavioral techniques have limited efficacy, topical therapies and selective serotonin reuptake inhibitors (SSRIs) show promise for effective treatment.

More Related Videos

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation
03:51

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation

Published on: December 8, 2023

5.3K
Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment
03:50

Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment

Published on: August 2, 2024

2.3K

Related Experiment Videos

Last Updated: Mar 27, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

1.3K
Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation
03:51

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation

Published on: December 8, 2023

5.3K
Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment
03:50

Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment

Published on: August 2, 2024

2.3K

Area of Science:

  • Urology
  • Andrology
  • Pharmacology

Background:

  • Premature ejaculation (PE) is the most common male sexual dysfunction, impacting 20-30% of men.
  • Current management strategies include behavioral techniques, which have shown limited short-term efficacy.

Purpose of the Study:

  • To review the literature on the management and treatment of premature ejaculation.
  • To evaluate the efficacy of various therapeutic approaches for premature ejaculation.

Main Methods:

  • A comprehensive literature search was conducted on PubMed from 2000 to the present.
  • Publications focusing on the management and treatment of premature ejaculation were retrieved and analyzed.

Main Results:

  • Behavioral techniques have historically been the primary approach for PE, but their short-term effectiveness is not well-established.
  • Topical therapies offer penile desensitization without altering ejaculatory sensation.
  • Selective serotonin reuptake inhibitors (SSRIs), known for causing delayed ejaculation, are frequently used off-label for PE treatment.
  • Dapoxetine, a short-acting SSRI specifically developed for PE, demonstrates promising results.

Conclusions:

  • Premature ejaculation management has evolved beyond traditional behavioral methods.
  • Pharmacological interventions, particularly SSRIs like dapoxetine, represent a significant advancement in treating premature ejaculation.
  • Further research into the efficacy and safety of newer treatments is warranted.