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Related Experiment Videos

Cerebral cavernous angioma in children.

A Fortuna1, L Ferrante, L Mastronardi

  • 1Dipartimento di Scienze Neurologiche, Università di Roma, Italy.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|August 1, 1989
PubMed
Summary

Pediatric cerebral cavernous angiomas are rare vascular malformations. This study details 56 cases, highlighting epilepsy and hemorrhagic syndrome as common clinical onsets in children.

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Area of Science:

  • Neurology
  • Pediatric Neurology
  • Vascular Malformations

Background:

  • Cerebral cavernous angiomas (CCAs) are uncommon vascular malformations.
  • Pediatric CCAs are exceedingly rare, with limited case studies available in literature.
  • This study contributes a series of pediatric cases to the existing body of knowledge.

Observation:

  • The incidence of pediatric CCAs peaks in two age groups: 0-2 years (26.8%) and 13-16 years (35.7%).
  • Clinical presentations include epilepsy (45.4%), hemorrhagic syndrome (27.3%), intracranial hypertension (16.4%), and focal neurological deficits (10.9%).
  • A total of 56 cases were analyzed, including 6 from the authors' series.

Findings:

  • Epilepsy is the most frequent clinical manifestation in pediatric CCAs.

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  • Hemorrhagic syndrome and intracranial hypertension are also significant presenting symptoms.
  • The study provides updated incidence data for specific pediatric age groups.

    • Implications:

    • Understanding the incidence and clinical presentation of pediatric CCAs is crucial for early diagnosis and management.
    • This research aids in recognizing the diverse neurological symptoms associated with pediatric CCAs.
    • The findings underscore the importance of considering CCAs in the differential diagnosis of neurological disorders in children.