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[Palilalia associated with progressive supranuclear palsy].

E Uyama, T Katahira, H Okada

Rinsho Shinkeigaku = Clinical Neurology

|May 1, 1989

Summary

Palilalia, a speech disorder involving word repetition, may not be rare in progressive supranuclear palsy (PSP). This condition might stem from a combination of extrapyramidal signs, pseudobulbar palsy, and dementia in PSP patients.

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Area of Science:

Neurology
Speech Pathology

Background:

Progressive supranuclear palsy (PSP) is a rare brain disorder that affects movement, vision, speech, and behavior.
Palilalia is a motor speech disorder characterized by compulsive repetition of words or phrases.

Observation:

Two cases of PSP presenting with palilalia are described.
Case 1: A 64-year-old woman with PSP exhibited compulsive word repetition, mental deterioration, and various neurological signs including supranuclear vertical gaze palsy and extrapyramidal signs.
Case 2: A 68-year-old woman with PSP showed less constant palilalia, alongside symptoms like double vision, slowness of movement, and cognitive decline.

Findings:

Palilalia was a notable symptom in both PSP cases, though varying in constancy.
Neurological examinations revealed overlapping signs of PSP, including cognitive impairment and motor deficits.

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The study suggests palilalia may be an underrecognized symptom in PSP.

Implications:

The findings suggest palilalia could be a more common feature of PSP than previously thought.
The pathogenesis of palilalia in PSP may involve the interplay of extrapyramidal signs, pseudobulbar palsy, and dementia.
Further research is warranted to understand the mechanisms and prevalence of palilalia in PSP.