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Infections due to Elizabethkingia meningoseptica in critically injured trauma patients: a seven-year study
N Rastogi1, P Mathur1, A Bindra2
1Department of Laboratory Medicine & Hospital Infection Control, JPNA Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.
Abstract:
Elizabethkingia meningoseptica is an infrequent cause of hospital-acquired infections. The clinical and microbiological profiles of infections due to E. meningoseptica over a seven-year period at a Level-I trauma centre are reported in this study. Medical records of patients from whose clinical samples E. meningoseptica was isolated on more than one occasion were reviewed. A total of 21 cases were observed during the study, 16 (76.2%) of which exhibited multidrug resistance. The observed in-hospital mortality rate was 47.6%. A high index of clinical suspicion and effective detection of E. meningoseptica in clinical samples are requisite for improved clinical outcome.
Insights
Elizabethkingia meningoseptica infections are rare but serious hospital-acquired infections. Multidrug resistance and high mortality rates highlight the need for early detection and clinical suspicion.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Hospital Epidemiology
Background:
- Elizabethkingia meningoseptica is an uncommon pathogen causing hospital-acquired infections.
- Data on clinical and microbiological profiles of E. meningoseptica infections are limited.
Purpose of the Study:
- To describe the clinical and microbiological characteristics of E. meningoseptica infections.
- To determine the outcomes of E. meningoseptica infections at a Level-I trauma center.
Main Methods:
- Retrospective review of medical records.
- Analysis of clinical samples positive for E. meningoseptica on multiple occasions.
- Seven-year study period at a Level-I trauma center.
Main Results:
- Twenty-one cases of E. meningoseptica infection were identified.
- Multidrug resistance was observed in 76.2% of cases.
- The in-hospital mortality rate was 47.6%.
Conclusions:
- E. meningoseptica infections are associated with significant morbidity and mortality.
- Effective detection and high clinical suspicion are crucial for improving patient outcomes.
- Multidrug resistance is a significant challenge in managing these infections.
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