Related Experiment Video

Updated: Mar 27, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.9K

A Review of Pediatric Chronic Kidney Disease

C D W Kaspar1, R Bholah, T E Bunchman

  • 1Virginia Commonwealth University, Division of Pediatric Nephrology, Richmond, VA, USA.

Blood Purification
|January 15, 2016
PubMed

Insights

Chronic kidney disease (CKD) presents differently in children and adults. This review highlights key distinctions in causes, related conditions, and care transitions for pediatric CKD patients.

Area of Science:

  • Nephrology
  • Pediatric Nephrology
  • Internal Medicine

Background:

  • Chronic kidney disease (CKD) affects both pediatric and adult populations.
  • Significant disparities exist in the presentation and management of CKD between these age groups.

Purpose of the Study:

  • To delineate the distinct characteristics of pediatric versus adult chronic kidney disease.
  • To identify unique challenges in pediatric CKD, including growth, quality of life, and adolescent-specific issues.

Main Methods:

  • Comprehensive literature review focusing on pediatric and adult CKD.
  • Comparative analysis of etiological factors, comorbidities, and treatment considerations.

Main Results:

  • Etiology, comorbidities, and disease impact on growth and quality of life differ markedly between pediatric and adult CKD.
  • Adolescent-specific issues and the transition to adult care present unique challenges.
  • Congenital anomalies of the kidney and urinary tract require special transplantation considerations in pediatric patients.

Conclusions:

  • Understanding the differences in pediatric and adult CKD is crucial for effective management.
  • Addressing age-specific challenges and transition of care is vital for improving outcomes in young CKD patients.
  • Specialized approaches are needed for transplantation in children with congenital kidney anomalies.

More Related Videos

Assessment of Vascular Function in Patients With Chronic Kidney Disease08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.9K
Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney08:53

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

Published on: August 9, 2014

45.7K

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
609
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
1.1K
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
596
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
936
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
372
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
1.4K