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Pleomorphic adenoma presenting with a mediastinal mass.

Young Kyung Lee1, Yee Hyung Kim2, Gou Young Kim3

  • 1Department of Radiology, Seoul Medical Center Seoul, Korea.

Thoracic Cancer
|January 15, 2016
PubMed
Summary

Pleomorphic adenoma, a common salivary gland tumor, rarely impacts the airway. This case details a bronchial pleomorphic adenoma with outward mediastinal growth, highlighting diagnostic imaging and pathology.

Keywords:
Chest CTendoscopic ultrasoundmediastinumpleomorphic adenoma

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Area of Science:

  • Pulmonology
  • Oncology
  • Pathology

Background:

  • Pleomorphic adenoma is the most common salivary gland neoplasm.
  • Airway involvement by pleomorphic adenoma is rare, typically presenting as an endobronchial mass.

Purpose of the Study:

  • To report a rare case of pleomorphic adenoma originating in the bronchus.
  • To describe its unusual outward growth into the mediastinum.
  • To correlate imaging findings with histopathology.

Main Methods:

  • Case presentation of a patient with a bronchial mass.
  • Review of computed tomography (CT) scans for anatomical detail.
  • Endoscopic ultrasound (EUS) for further characterization.
  • Histopathological examination for definitive diagnosis.

Main Results:

  • A pleomorphic adenoma was identified originating from the bronchus.
  • The tumor demonstrated extraluminal growth into the mediastinum.
  • CT and EUS provided key insights into the mass's extent and characteristics.
  • Histopathology confirmed the diagnosis of pleomorphic adenoma.

Conclusions:

  • Pleomorphic adenoma can rarely arise in the bronchus.
  • Unusual growth patterns, such as extraluminal extension, can occur.
  • Multimodality imaging (CT, EUS) and histopathology are crucial for diagnosis and management.