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[Optimization of Extraction Technology for Sericin from Silkworm Cocoon with Orthogonal Design]
Objective:
To optimize the appropriate extracting technology for sericin from Silkworm cocoon.
Methods:
Using sericin extraction rates and sericin content as the indices. The single and orthogonal experiments were used to determine the best conditions.
Results:
The optimal extraction technology for sericin from Silkworm cocoon was as follows: 1: 30 for the ratio of solid to liquid, 3 h reflux for 2 times of extraction and water temperature at 100 degrees C. The extraction rate of sericin from Silkworm cocoon was 27.1%.
Conclusion:
The optimal extraction technology is stable, feasible, and can provide reference for further pharmacological study on cocoon sericin.
