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[Study on Effective Parts of Ficus microcarpa Leaves by Serum HPLC Fingerprint]
Objective:
To study the relevance between the drug effects and serum HPLC fingerprint of chemical constituents in blood from Ficus microcarpa leaves.
Methods:
Fingerprints of the preparation and drug-containing serum of rats were established by HPLC. Based on the fingerprints, chemical constituents in blood were investigated.
Results:
There were seven common peaks in the HPLC fingerprints of drug-containing serum of rats. Polarity fraction of the chemical constituents in blood existed in the ethyl acetate extract, and five fingerprint peaks of serum HPLC fingerprint existed in n-butanol extract.
Conclusion:
Determination of the component groups in blood provides some data on material basis study in vivo for Ficus microcarpa leaves.
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