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Respiratory complications of the rheumatological diseases in childhood
Anne E Richardson1, Kishore Warrier1, H Vyas2
1Department of Paediatrics, Nottingham University Hospitals, Nottingham, UK.
Insights
Pediatric rheumatological diseases can cause rare but serious lung complications. Early detection and multidisciplinary care improve outcomes for children with these conditions.
Area of Science:
- Pediatric Rheumatology
- Pulmonology
- Internal Medicine
Background:
- Pleuropulmonary manifestations of pediatric rheumatological diseases are uncommon but increase morbidity and mortality.
- Common conditions include juvenile systemic lupus erythematosus, scleroderma, juvenile dermatomyositis, mixed connective tissue disease, granulomatosis with polyangitis, and juvenile idiopathic arthritis.
Purpose of the Study:
- To review the literature on respiratory complications in common pediatric rheumatological diseases.
- To highlight the importance of early detection and multidisciplinary management for optimal patient outcomes.
Main Methods:
- Literature review of pleuropulmonary manifestations in pediatric rheumatological diseases.
- Analysis of the role of pulmonary function testing in diagnosis and monitoring.
Main Results:
- Pulmonary function testing aids in differential diagnosis and assessing disease severity.
- Early identification of pulmonary involvement is crucial for timely and effective treatment.
Conclusions:
- Prompt and targeted therapies, guided by early detection, are essential for managing respiratory complications.
- Joint specialist pediatric rheumatology and respiratory reviews in a multidisciplinary setting are recommended for best outcomes.
Abstract:
Pleuropulmonary manifestations of rheumatological diseases are rare in children but pose a significant risk to overall morbidity and mortality. We have reviewed the literature to provide an overview of the respiratory complications of the commonest rheumatological diseases to occur in children (juvenile systemic lupus erythematosus, scleroderma, juvenile dermatomyositis, mixed connective tissue disease, granulomatosis with polyangitis and juvenile idiopathic arthritis). Pulmonary function testing in these patients can be used to refine the differential diagnosis and establish disease severity, but also has a role in ongoing monitoring for respiratory complications. Early detection of pulmonary involvement allows for prompt and targeted therapies to achieve the best outcome for the child. This is best achieved with joint specialist paediatric rheumatology and respiratory reviews in a multidisciplinary setting.
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