Related Experiment Video
Updated: Mar 27, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Adding innovative practices and technology to central line bundle reduces bloodstream infection rate in challenging
Marianne Pavia1, Marianne Mazza1
1St. Mary's Healthcare System for Children, Bayside, NY.
Insights
A pediatric hospital reduced bloodstream infections (BSIs) in short bowel syndrome patients using an alcohol disinfection cap and additional interventions. Both the cap-only and multipronged approaches significantly lowered BSI rates.
Area of Science:
- Pediatric Medicine
- Infectious Disease Control
- Hospital Epidemiology
Background:
- Short bowel syndrome (SBS) patients in specialized pediatric hospitals face high bloodstream infection (BSI) risk.
- Fecal residue and frequent intravenous (IV) line access are key contributors to BSI in this vulnerable population.
Purpose of the Study:
- To evaluate the effectiveness of infection control interventions in reducing BSIs among pediatric SBS patients.
- To compare the impact of a single intervention (disinfection cap) versus a multipronged approach.
Main Methods:
- Implementation of an alcohol-dispensing disinfection cap for IV lines.
- Addition of three further interventions following the initial cap implementation.
- Monitoring of BSI rates during the cap-only phase and the subsequent multipronged phase.
Main Results:
- The alcohol-disinfection cap-only phase demonstrated a reduction in BSI rates.
- The subsequent multipronged intervention phase also achieved a significant decrease in hospital-acquired BSIs.
- Both intervention strategies proved successful in lowering the overall BSI rate.
Conclusions:
- Targeted infection control measures, including disinfection caps, are effective in reducing BSIs in pediatric SBS patients.
- A multipronged approach can further enhance BSI reduction efforts.
- These findings support the adoption of similar strategies in high-risk pediatric populations.
Abstract:
A specialized pediatric hospital serves many patients with short bowel syndrome. The patients' fecal residue plus frequent access of intravenous lines increases bloodstream infection (BSI) risk. To reduce BSIs, the hospital first implemented an alcohol-dispensing disinfection cap and then added 3 more interventions, with both the cap-only phase and the multipronged phase successfully lowering the hospital's BSI rate.
Related Concept Videos
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Endocarditis IV: Nursing Management
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Cardiac Catheterization IV: Nursing Management
Nursing Clinical Information System
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...

