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Draft Genome Sequence of an Enterobacter Species Associated with Illnesses and Powdered Infant Formula

Emily E Jackson1, Pauline Ogrodzki1, Ben Pascoe2

  • 1Pathogen Research Group, School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom.

Genome Announcements
|January 16, 2016
PubMed

Insights

This study reports the first draft genome sequence of an Enterobacter strain potentially transmitted from powdered infant formula (PIF) to infants, causing illness. Current PIF microbiological criteria may require updates due to this strain

Area of Science:

  • Microbiology
  • Genomics
  • Food Safety

Background:

  • Enterobacter species are currently permitted in powdered infant formula (PIF).
  • Concerns exist regarding the potential for microbial contamination in PIF.
  • Infant formula is a critical source of nutrition for vulnerable infants.

Purpose of the Study:

  • To report the draft genome sequence of an Enterobacter strain.
  • To investigate the potential transmission of this strain from PIF to infants.
  • To assess the implications for current PIF microbiological criteria.

Main Methods:

  • Draft genome sequencing of the identified Enterobacter strain.
  • Analysis of genomic data to characterize the strain.
  • Review of existing microbiological criteria for PIF.

Main Results:

  • The first draft genome sequence of an Enterobacter species linked to infant illness is presented.
  • Evidence suggests potential transmission from powdered infant formula (PIF).
  • The identified strain highlights a possible gap in PIF safety standards.

Conclusions:

  • The findings necessitate a re-evaluation of microbiological criteria for PIF.
  • Stricter controls may be required to prevent pathogen transmission through infant formula.
  • Genomic sequencing is crucial for tracking foodborne pathogens.

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