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Observations on the curative effect of lactulose for postpartum constipation based on a large sample study
Yu Zhou1, Xinghua Yang2, Ling Fan3
1Department of Obstetrics, Shandong Province Hospital Jinan 250014, Shandong, China.
International Journal of Clinical and Experimental Medicine
|January 16, 2016
Summary
Lactulose effectively treats postpartum constipation, improving symptoms like stool consistency and frequency. This treatment showed sustained benefits even after medication cessation, indicating its safety and efficacy for new mothers.
Area of Science:
- Obstetrics and Gynecology
- Gastroenterology
- Pharmacology
Background:
- Postpartum constipation is a common issue affecting women after childbirth.
- Effective and safe interventions are needed to manage this condition.
Purpose of the Study:
- To evaluate the efficacy and safety of lactulose as an intervention for postpartum constipation.
Main Methods:
- A multicenter clinical survey involving 4781 postpartum women treated with lactulose oral solution.
- Monitoring of constipation symptoms and routine blood, urine, and stool examinations before and after a 2-week intervention, with a 4-week follow-up.
Main Results:
- Significant improvements observed in stool consistency, daily defecation frequency, defecation time, and dyschezia.
- Therapeutic benefits persisted post-intervention.
- Decreased trend in abnormal rates across blood, urine, and stool examinations.
Conclusions:
- Lactulose demonstrates significant therapeutic benefits for postpartum constipation.
- It can be developed as an effective intervention for this patient population.
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