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High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
Who is watching the watchmen: Is quality reporting ever harmful?
R Scott Braithwaite1, Arthur Caplan2
1Division of Comparative Effectiveness and Decision Science, Department of Population Health, School of Medicine, New York University, New York, NY, USA.
Quality reporting systems need minimum accuracy standards to prevent harm. Even with perfect performance, a specific threshold ensures quality measures improve health outcomes, avoiding negative consequences like patient cherry-picking.
Area of Science:
- Health services research
- Health economics
- Biostatistics
Background:
- Quality reporting incentivizes healthcare providers to improve patient outcomes.
- Current systems may lead to unintended consequences like patient cherry-picking or underpowered comparisons.
- No established minimum accuracy standards exist for quality reporting measures.
Purpose of the Study:
- To delineate minimal accuracy standards for quality measures.
- To establish a prerequisite for effective and ethical quality reporting.
Main Methods:
- A decision analytic model was employed.
- Simplified assumptions were used to illustrate minimal standards.
Main Results:
- A minimal accuracy level was identified to ensure quality reporting "does no harm."
- This threshold depends on the gain in health-related quality of life versus patient switching behavior.
- Optimal system performance (sensitivity and specificity of 1) was assumed.
Conclusions:
- Quality measurement systems must demonstrate improved health outcomes.
- A specific standard of measurement accuracy is necessary for systems not yet proven to enhance health.
- Ensuring accuracy is crucial to prevent harm from quality reporting initiatives.
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