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Updated: Mar 27, 2026

The Isolation and Characterization of Low- and Normal- Density Neutrophils from Whole Blood
Published on: February 7, 2025
Neutrophil-lymphocyte ratio is associated with low high-density lipoprotein cholesterol in healthy young men
Duran Tok1, Sinan Iscen2, Salim Ozenc3
1Healthy Service Command, Turkish Armed Forces, Ankara, Turkey.
Objective:
It has been reported that the neutrophil-lymphocyte ratio is significantly elevated in patients with low high-density lipoprotein cholesterol (<35 mg/dL). But in this study, some patients had hypertension that may have affected the neutrophil-lymphocyte ratio. This study consisted of 1274 asymptomatic healthy young men. In contrast with the previous study, we investigated the neutrophil-lymphocyte ratio in healthy young men with low high-density lipoprotein cholesterol compared with controls.
Methods:
We studied 1274 asymptomatic young males (military personnel screening) who underwent routine health check-up. Of them, 102 subjects had low high-density lipoprotein cholesterol.
Results:
The neutrophil-lymphocyte ratio was significantly higher among the men with low high-density lipoprotein cholesterol than that of the control group (P < 0.001).
Conclusion:
We conclude that the neutrophil-lymphocyte ratio is significantly elevated in asymptomatic healthy young men with low high-density lipoprotein cholesterol compared with control participants.
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