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Cell Proliferation in Neuroblastoma
Laura L Stafman1, Elizabeth A Beierle2
1Department of Surgery, Division of Pediatric Surgery, University of Alabama, Birmingham, AL 35233, USA. lstafman@uabmc.edu.
Cancers
|January 16, 2016
Abstract:
Neuroblastoma, the most common extracranial solid tumor of childhood, continues to carry a dismal prognosis for children diagnosed with advanced stage or relapsed disease. This review focuses upon factors responsible for cell proliferation in neuroblastoma including transcription factors, kinases, and regulators of the cell cycle. Novel therapeutic strategies directed toward these targets in neuroblastoma are discussed.

