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Updated: Mar 27, 2026
Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
Published on: February 23, 2024
RECENT ADVANCES IN BIOMARKERS IN SEVERE BURNS
Mireia Ruiz-Castilla1, Oriol Roca, Joan R Masclans
1*Plastic and Reconstructive Surgery Department and Burns Unit, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Barcelona †Surgery Department, Universitat Autònoma de Barcelona, Bellaterra ‡Critical Care Department, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Barcelona §Ciber Enfermedades Respiratorias (Ciberes), Instituto de Salud Carlos III, Madrid ||Critical Care Department, Parc de Salut Mar (Hospital del Mar) de Barcelona, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
Abstract:
The pathophysiology of burn injuries is tremendously complex. A thorough understanding is essential for correct treatment of the burned area and also to limit the appearance of organ dysfunction, which, in fact, is a key determinant of morbidity and mortality. In this context, research into biomarkers may play a major role. Biomarkers have traditionally been considered an important area of medical research: the measurement of certain biomarkers has led to a better understanding of pathophysiology, while others have been used either to assess the effectiveness of specific treatments or for prognostic purposes. Research into biomarkers may help to improve the prognosis of patients with severe burn injury. The aim of the present clinical review is to discuss new evidence of the value of biomarkers in this setting.
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