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Paternity calculations from DNA multilocus profiles.

I W Evett, D J Werrett, J S Buckleton

    Journal - Forensic Science Society
    |July 1, 1989
    PubMed
    Summary
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    This study presents a straightforward method for analyzing DNA profiles to resolve paternity disputes. The approach, using multilocus probes, has proven effective in casework for determining biological relationships.

    Area of Science:

    • Forensic Science
    • Genetics
    • Molecular Biology

    Background:

    • DNA profiling using multilocus probes is crucial for establishing biological relationships.
    • Disputed parentage cases require reliable methods for DNA analysis.

    Purpose of the Study:

    • To describe a simple approach for analyzing DNA profiles in disputed paternity cases.
    • To demonstrate the utility of this method in casework.

    Main Methods:

    • Analysis of DNA profiles from mother, child, and putative father.
    • Utilizing multilocus probes for DNA fingerprinting.
    • Illustration with a numerical example calculated on a computer spreadsheet.

    Main Results:

    • The described approach provides valuable evidence in disputed parentage cases.

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  • The method has shown utility in practical casework, even without accounting for mutant bands.

    • Conclusions:

    • A simple DNA profile analysis method can effectively aid in resolving paternity disputes.
    • This technique offers a practical tool for forensic casework in parentage testing.