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Is there an association between colonization with group B Streptococcus and prematurity?
1Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut 06510.
The Journal of Reproductive Medicine
|October 1, 1989
Summary
Group B Streptococcus (GBS) genital tract colonization is not linked to prematurity. However, GBS asymptomatic bacteriuria in pregnant women is associated with a higher rate of premature birth.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Neonatal Health
Background:
- Group B Streptococcus (GBS) is a common bacterium.
- GBS colonization can occur in the genitourinary tract.
- Prematurity remains a significant concern in neonatal health.
Purpose of the Study:
- To investigate the association between genitourinary tract colonization with GBS and prematurity.
- To synthesize existing research on GBS and preterm birth.
Main Methods:
- A comprehensive literature search was performed.
- Ten studies were critically reviewed.
- Studies focused on either genital colonization or asymptomatic bacteriuria.
Main Results:
- Six of seven studies found no association between GBS cervicovaginal colonization and prematurity.
- Three studies on asymptomatic bacteriuria indicated a higher prematurity rate in GBS-infected women.
- GBS bacteriuria, not genital colonization, showed a link to preterm birth.
Conclusions:
- Current evidence does not support a link between GBS genital colonization and prematurity.
- GBS asymptomatic bacteriuria may be a risk factor for prematurity.
- Further research may clarify the role of GBS in preterm birth.