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Updated: Mar 27, 2026

Virtual Agent for Real-Time Motivational Interviewing by Integrating Adaptive Nonverbal Behavior and Language Models
Published on: December 23, 2025
Effect of motivational interviewing on quality of life in patients with epilepsy
Nazafarin Hosseini1, Somaye Mokhtari2, Ebrahim Momeni2
1Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Objective:
In this study, the effect of motivational interviewing on quality of life was evaluated in patients with epilepsy.
Methods:
Fifty-six patients with epilepsy in a clinical trial were randomly assigned to intervention and control groups. Motivational interviewing during 5 sessions was applied for the intervention group, and the control group received health-care services. Quality-of-life questionnaire in epilepsy (QOLIE-89) was applied as pre- and posttest for both groups. Before and two months after intervention, both groups were assessed. Data were analyzed by independent t-test, Chi-square test, and paired t-test.
Results:
The data analysis showed that mean score of the QOLIE-89 was 38.94±8.55 and 70.90±7.99 in the intervention group before and after the intervention, respectfully, and 44.59±12.27 and 36.52±7.16 in the control group sequentially. The intervention group showed a significant score increase in their quality of life (p<0.001), whereas the control group had a score decrease (p<0.001).
Conclusion:
Motivational interviewing approach could be used as an effective intervention method for improving patients' quality of life.
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