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Necrotizing fasciitis.

S M Roser, A W Chow, F A Brady

    Journal of Oral Surgery (American Dental Association : 1965)
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Necrotizing fasciitis, a severe soft tissue infection, involves rapid tissue death. Penicillin effectively treated all identified aerobic and anaerobic bacteria in a case originating from a dental infection.

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    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Oral Surgery

    Background:

    • Necrotizing fasciitis is a severe, uncommon soft tissue infection.
    • Characterized by rapid, widespread fascial necrosis and undermining of soft tissue.
    • Anaerobic organisms play a crucial role in its pathogenesis.

    Observation:

    • A case of necrotizing fasciitis originated from a periapically infected mandibular third molar.
    • Aerobic and anaerobic organisms were isolated from the infection site.
    • All isolated organisms showed in vitro sensitivity to penicillin.

    Findings:

    • Advances in anaerobic culture techniques have improved pathogen identification.
    • The study highlights the role of mixed aerobic and anaerobic infections.

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  • Penicillin demonstrated broad-spectrum efficacy against the isolated pathogens.

    • Implications:

    • Early antibiotic therapy, particularly with penicillin, is vital for treating necrotizing fasciitis.
    • Radical surgical incision and drainage remain critical treatment components.
    • Understanding the polymicrobial nature of this infection aids therapeutic strategies.