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Updated: Mar 27, 2026

In Vivo Three-Dimensional Two-Photon Microscopy to Study Conducted Vascular Responses by Local ATP Ejection Using a Glass Micro-Pipette
Published on: June 7, 2019
Observation of vasculature alternation by intense pulsed light combined with physicochemical methods
Taeyoon Son1, Heesung Kang2, Byungjo Jung3
1Department of Bioengineering, University of Illinois at Chicago, USA.
Abstract:
Intense pulsed light (IPL) with low energy insufficient to completely destroy a vasculature was applied to rabbit ears to investigate vasculature alteration. Glycerol was combined with IPL to enhance the transfer efficacy of IPL energy. Both trans-illumination and laser speckle contrast images were obtained and analyzed after treatment. The application of IPL and glycerol combination induced vasodilation and improvement in blood flow. Moreover, such phenomenon was maintained over time. IPL may be applied to treat blood circulatory diseases by inducing vasodilation and to improve blood flow.
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