Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA
M Horikoshi1, C K Wang, H Fujii
1Laboratory of Biochemistry and Molecular Biology, Rockefeller University, New York, New York 10021.
Nature
|September 28, 1989
Abstract:
The TATA sequence-binding factor TFIID plays a central role both in promoter activation by RNA polymerase II and other common initiation factors, and in promoter regulation by gene-specific factors. The sequence of yeast TFIID, which seems to be encoded by a single gene, contains interesting structural motifs that are possibly involved in these functions, and is similar to sequences of bacterial sigma factors.
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